The Isotopes will be on the outdoor TJ Ryan's Stage at 6pm to raise money for the Arc of Monroe and The Pirate Toy Fund.  We're just as...

The Isotopes invade Irondequoit's insatiable music fest, Hoochenanny!  We're playing on Saturday in between the Tennessee mouthwash and the white lightnin'.  Get yer tickets at hoochenanny.com  

Come join The Isotopes and all their friend(s) as they play your favorite song(s) at the annual karaoke extravaganza!  $10 advance, %15 door, get your tix here

The 'Topes return to Buffalo to visit our bestest buds at Flying Bison Brewery for a Saturday afternoon of suds, surf, and succotash.  (Don't quote me on that...

The Isotopes bring holiday cheer and a preview of the holiday show to the Roc Holiday village to celebrate the holiday season!

Santa's favorite band at Jesus's favorite brewery?  Truly a Christmas miracle.

First show of the year!  Come join us at Johnny's Irish Pub for a night you won't remember.

The Isotopes return to Skylark Lounge for... reasons

The 'Topes rock Saturday afternoon at WNY's whiskeyest festival with locals Head to the Roots, Ocular Panther and Candy, and national acts Grace Bowers, Tommy Brunett, Guster and...